A9519

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

≥98% (TLC)

• Sinonimo/i: Adjuvant Peptide, Muramyl dipeptide
• Formula empirica (notazione di Hill): C₁₉H₃₂N₄O₁₁ · xH₂O
• Numero CAS: 53678-77-6
• Peso molecolare: 492.48 (anhydrous basis)
• Beilstein: 4220745
• Numero CE: 258-696-9
• Numero MDL: MFCD00077638
• Codice UNSPSC: 12352209
• ID PubChem: 24891464
• NACRES: NA.26

Proprietà

• Livello qualitativo: 200
• Saggio: ≥98% (TLC)
• Forma fisica: powder
• tecniche: ligand binding assay: suitable
• Colore: white
• applicazioni: cell analysis
• Temperatura di conservazione: −20°C
• Stringa SMILE: C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
• InChI: 1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19?/m0/s1; BSOQXXWZTUDTEL-QAQREVAFSA-N

Descrizione

Amino Acid Sequence

MurNAc-Ala-Agn

Applicazioni

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.

Azioni biochim/fisiol

Enhances antigenicity of weak antigens, increasing antibody titer.

Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.

N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP, muramyl dipeptide), a neurotrophic and immunomodulatory factor related to bacterial peptidoglycans, is used as an immune modulation factor that enhances immune response and to study neural development.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)