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X4002

Sigma-Aldrich

Xantina

BioUltra, ≥99%

Sinonimo/i:

2,6-diidrossipurina

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About This Item

Formula empirica (notazione di Hill):
C5H4N4O2
Numero CAS:
69-89-6
Peso molecolare:
152.11
Beilstein:
8733
Numero CE:
200-718-6
Numero MDL:
MFCD00078453
Codice UNSPSC:
41106305
ID PubChem:
24902144
NACRES:
NA.51

Origine biologica

synthetic (organic)

Nome Commerciale

BioUltra

Saggio

≥99%

Forma fisica

powder

Impurezze

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

Residuo alla calcinazione

≤0.1%

Solubilità

1 M NaOH: 0.1 M, clear, colorless to light yellow

Anioni in tracce

sulfate (SO42-): <0.05%

Cationi in tracce

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

Stringa SMILE

O=C1NC(=O)c2nc[nH]c2N1

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
LRFVTYWOQMYALW-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:
  • Guanine deamination by guanine deaminase
  • Hypoxanthine conversion by xanthine oxidoreductase
Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.

Applicazioni

Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:
  • yeast culture
  • human cell line culture
  • recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

Azioni biochim/fisiol

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.

Caratteristiche e vantaggi

  • Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
  • Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

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Guanine

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Free radical biology & medicine, 53(10), 1960-1967 (2012-09-18)
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R Hille et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 9(11), 995-1003 (1995-08-01)
Xanthine oxidase and xanthine dehydrogenase are enzymes involved in the metabolism of purines and pyrimidines in various organisms. Their relationship to one another has been the subject of considerable debate, primarily because of their proposed roles in ischemia/reperfusion damage in
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Articoli

HPLC Analysis of Xanthines on Purospher® STAR RP-18 endcapped

Xanthine is a purine base found in most human body tissues and fluids as well as in other organisms. Methylated xanthines (methylxanthines), which include caffeine, paraxanthine, theobromine, and theophylline, commonly used for their effects as mild stiµlants and as bronchodilators, notably in the treatment of asthma symptoms. This application shows the efficient separation of several common xanthines and may be applied their analysis in any number of desired matrices.

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