W108

WAY-100635 maleate salt

powder

• Sinonimo/i: N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt
• Formula empirica (notazione di Hill): C₂₅H₃₄N₄O₂ · C₄H₄O₄
• Numero CAS: 634908-75-1
• Peso molecolare: 538.64
• Numero MDL: MFCD01321056
• Codice UNSPSC: 12352200
• ID PubChem: 24278113
• NACRES: NA.77

Proprietà

• Stato: powder
• Livello qualitativo: 100
• Colore: white
• Solubilità: H₂O: 25 mg/mL
• Stringa SMILE: [H]\C(=C(/[H])C(O)=O)C(O)=O.COc1ccccc1N2CCN(CC2)CCN(C(=O)C3CCCCC3)c4ccccn4
• InChI: 1S/C25H34N4O2.C4H4O4/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21;5-3(6)1-2-4(7)8/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-; XIGAHNVCEFUYOV-BTJKTKAUSA-N
• Informazioni sul gene: human ... HTR1A(3350)

Descrizione

Applicazioni

WAY-100635 maleate salt has been used as a 5-HT1A serotonin receptor antagonist:

• to study whether the behavior of the cleaner wrasse is regulated by serotonin activity
• to block activity of 3,4 methylenedioxymethamphetamine (MDMA) used to induce oxytocin release in male Wistar rats to increase their social behavior
• to study the role of serotonin during metamorphosis of the ascidian Phallusia mammillata larvae

Azioni biochim/fisiol

WAY-100635 maleate salt is a highly selective 5-HT1A serotonin receptor antagonist. It has an ability to inhibit brexpiprazole, an antipsychotic drug that regulates serotonin-dopamine activity.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)