T7165
Tyrphostin 23
≥98%
Sinonimo/i:
(3,4-Dihydroxybenzylidene)malononitrile, RG-50810
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About This Item
Formula empirica (notazione di Hill):
C10H6N2O2
Numero CAS:
Peso molecolare:
186.17
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77
Prodotti consigliati
Origine biologica
synthetic (organic)
Livello qualitativo
Saggio
≥98%
Stato
powder
Potenza
35 μM IC50
Solubilità
DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow
Temperatura di conservazione
2-8°C
Stringa SMILE
Oc1ccc(cc1O)\C=C(\C#N)C#N
InChI
1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
VTJXFTPMFYAJJU-UHFFFAOYSA-N
Informazioni sul gene
human ... CDK2(1017)
Applicazioni
Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils.
Azioni biochim/fisiol
Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
Caratteristiche e vantaggi
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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