T1428
apo-Transferrin bovine
BioReagent, suitable for cell culture, ≥98%
Sinonimo/i:
Human serotransferrin
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About This Item
Prodotti consigliati
Origine biologica
bovine
Livello qualitativo
Nome Commerciale
BioReagent
Saggio
≥98%
Stato
powder
tecniche
cell culture | mammalian: suitable
Impurezze
iron, essentially free
Solubilità
H2O: 10 mg/mL
N° accesso UniProt
Temperatura di conservazione
2-8°C
Informazioni sul gene
bovine ... TF(280705)
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Descrizione generale
apo-Transferrin is an iron-free form of transferrin that is present in circulation.
Applicazioni
All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.
apo-Transferrin bovine has been used as a component of:
- basal medium for culturing bovine mammary epithelial cells
- minimum essential medium α (MEM-α) for spermatogonial stem cells (SSCs) culture
- induction medium for mesenchymal stem cell culture
Azioni biochim/fisiol
apo-Transferrin (apoTf) aids in preventing iron accumulation in tissues, especially in non-transfusion dependent β-thalassemia.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I clienti hanno visto anche
Monique P Gelderman et al.
Haematologica, 100(5), 611-622 (2015-01-27)
Intermediate beta-thalassemia has a broad spectrum of sequelae and affected subjects may require occasional blood transfusions over their lifetime to correct anemia. Iron overload in intermediate beta-thalassemia results from a paradoxical intestinal absorption, iron release from macrophages and hepatocytes, and
Keita Abe et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 63(1-2), 154-156 (2008-04-05)
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