T0251
Thymidine 5′-triphosphate sodium salt
≥96%
Sinonimo/i:
TTP, dTTP
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About This Item
Formula empirica (notazione di Hill):
C10H16N2O14P3Na
Numero CAS:
Peso molecolare:
504.15
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51
Prodotti consigliati
Livello qualitativo
Saggio
≥96%
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Stringa SMILE
[NaH].[P](=O)(O[P](=O)(OCC1OC(CC1O)N2C=C(C(=O)NC2=O)C)O)(O[P](=O)(O)O)O
InChI
1S/C10H17N2O14P3.Na.H/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;
KAELIXTVSANDSE-UHFFFAOYSA-N
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Applicazioni
Thymidine 5′-triphosphate (dTTP) is one of the four natural deoxynucleotides, along with deoxyadenosine 5′-triphosphate (dATP), deoxyguanosine 5′-triphosphate (dGTP) and deoxycytosine 5′-triphosphate (dCTP) used for the biosynthesis of deoxyribonucleic acids by DNA polymerases and reverse transcriptases. Deoxy-TTP may also be used as a substrate to study the specificity and kinetics of thymidine-triphosphatase(s) (EC 3.6.1.39) and other dTTP hydrolyzing activities.
Thymidine 5′-triphosphate sodium salt has been used:
- in the quenching ability test for dual-aptamer and multiple-nucleotide detection based on a multiple-aptamer/GO-nS complex
- to study protein-metabolite interactions in the central metabolism of Escherichia coli
- in a polymerase chain reaction (PCR) product formation using AM-toxin primers
Azioni biochim/fisiol
Thymidine triphosphate is a building block of DNA. It acts as an allosteric regulator of other nucleotides′ metabolism.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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