SML1169
Pitstop 2
≥98% (HPLC), powder, clathrin-mediated endocytosis inhibitor
Sinonimo/i:
N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamide, Pitstop-2
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About This Item
Formula empirica (notazione di Hill):
C20H13BrN2O3S2
Numero CAS:
Peso molecolare:
473.36
Codice UNSPSC:
12352200
NACRES:
NA.77
Prodotti consigliati
Nome del prodotto
Pitstop 2, ≥98% (HPLC)
Livello qualitativo
Saggio
≥98% (HPLC)
Stato
powder
Colore
white to light brown
Solubilità
DMSO: 20 mg/mL, clear
Temperatura di conservazione
−20°C
Applicazioni
Pitstop 2 has been used as an inhibitor of clathrin-mediated endocytosis.
Azioni biochim/fisiol
Pitstop 2 also has an ability to breakdown the nuclear pore complex (NPC) permeability barrier and decrease importin β binding along with alteration of the NPC ultrastructure. Pitstop 2 is also involved in the inhibition of platelet activation, platelet aggregation and secretion.
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis that acts via blocking ligand access to the clathrin terminal domain. Pitstop 2 selectively inhibits clathrin-mediated HIV entry and stalls clathrin-coated pit (CCP) dynamics.
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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