SCP0020
[Sar1]-Angiotensin II
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About This Item
Formula empirica (notazione di Hill):
C49H71N13O10
Peso molecolare:
1002.17
Codice UNSPSC:
12352209
NACRES:
NA.32
Prodotti consigliati
![[Asn1, Val5]-Angiotensin II ≥97% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/380/827/d4959a32-f11c-488c-9bc0-86d4d43cb5cb/640/d4959a32-f11c-488c-9bc0-86d4d43cb5cb.png)
![[Val5]-Angiotensin II acetate salt hydrate ≥95% (HPLC), powder](/deepweb/assets/sigmaaldrich/product/structures/301/478/c093dfb8-a891-46ac-b6a1-655b77da7c03/640/c093dfb8-a891-46ac-b6a1-655b77da7c03.png)
Saggio
≥95% (HPLC)
Stato
lyophilized
Composizione
Peptide Content, ≥65%
Condizioni di stoccaggio
protect from light
Temperatura di conservazione
−20°C
Amino Acid Sequence
Sar-Arg-Val-Tyr-Ile-His-Pro-Phe
Applicazioni
Angiotensins are peptide hormone components of the renin-angiotensin system involved in the regulation of blood vessel constriction and aldosterone release. Angiotensin I, a decapeptide derived from angiotensinogen, is a converted to Angiotensin II by the removal of the two C-terminal amino acids. Various analogues of Angiotensins I and II made by amino acid substitution are used in structure and sequence studies to analyze and differentiate the functions of natural angiotensins.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Novel concept in the mechanism of injury and protection of gastric mucosa: role of Renin-Angiotensin system and active metabolites of Angiotensin.
Brzozowski T, Ptak-Belowska A, et al.
Current Medicinal Chemistry, 16, 55-62 (2012)
Vani X Oliveira et al.
Regulatory peptides, 172(1-3), 1-7 (2011-07-27)
Angiotensin II (AII) is the active octapeptide product of the renin enzymatic cascade, which is responsible for sustaining blood pressure. In an attempt to establish the AII-receptor-bound conformation of this octapeptide, we designed conformationally constrained analogues by scanning the entire
Mauricio Sendeski et al.
Radiology, 251(3), 697-704 (2009-04-16)
To determine whether a type of contrast medium (CM), iodixanol, modifies outer medullary descending vasa recta (DVR) vasoreactivity and nitric oxide (NO) production in isolated microperfused DVR. Animal handling conformed to the Animal Care Committee Guidelines of all participating institutions.
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