S5013

Salbutamol hemisulfate salt

≥98%

• Sinonimo/i: α-([t-Butylamino]methyl)-4-hydroxy-m-xylene-α,α′-diol, Albuterol
• Formula condensata: C₁₃H₂₁NO₃ · 1/2H₂SO₄
• Numero CAS: 51022-70-9
• Peso molecolare: 288.35
• Numero CE: 256-916-8
• Numero MDL: MFCD00055200
• Codice UNSPSC: 12352200
• ID PubChem: 24277746
• NACRES: NA.77

Proprietà

• Livello qualitativo: 200
• Saggio: ≥98%
• Solubilità: 1 M NaOH: 50 mg/ml, clear to slightly hazy, yellow-green
• Ideatore: GlaxoSmithKline
• Stringa SMILE: OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2
• InChI: 1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4); BNPSSFBOAGDEEL-UHFFFAOYSA-N
• Informazioni sul gene: human ... ADRB2(154)

Descrizione

Applicazioni

Salbutamol hemisulfate salt has been used as reference standards of drugs for the validation of β-agonist residue.

Salbutamol hemisulfate salt was used as standard in analysis of fortified meat for LABA content using ELISA kits.³ It was used to study the response of prostaglandin 2α to various β-adrenergic agonists in cultured bovine endometrial cells.⁴

Azioni biochim/fisiol

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP). Salbutamol is particularly effective in treatment of asthma as it provides immediate relief. Salbutamol is one of the most popular short-acting BA (SABA). It is useful in treating the symptoms of EIB (exercise induced bronchospasm).

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).¹ Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.²

β2-Adrenergic receptor agonist.

Caratteristiche e vantaggi

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317,H351,H361fd
• Consigli di prudenza: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Classi di pericolo: Carc. 2 - Repr. 2 - Skin Sens. 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)