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S1002

Sigma-Aldrich

Saccharin sodium salt hydrate

≥98.0% (titration)

Sinonimo/i:

2,3-Dihydro-3-oxobenzisosulfonazole sodium salt, 2-Sulfobenzoic acid imide sodium salt, o-Sulfobenzimide sodium salt, Saccharin soluble

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About This Item

Formula empirica (notazione di Hill):
C7H4NNaO3S · xH2O
Numero CAS:
82385-42-0
Peso molecolare:
205.17 (anhydrous basis)
Beilstein:
3599229
Numero CE:
204-886-1
Numero MDL:
MFCD00149605
Codice UNSPSC:
12164504
ID PubChem:
24899456
NACRES:
NA.25
Saggio:
≥98.0% (titration)

Livello qualitativo

200

Saggio

≥98.0% (titration)

Dolcezza

300 × sucrose

Stringa SMILE

[Na+].[H]O[H].[O-]C1=NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S.Na.H2O/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;;/h1-4H,(H,8,9);;1H2/q;+1;/p-1
ILJOYZVVZZFIKA-UHFFFAOYSA-M

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Applicazioni


  • Application of a colorimetric technique in quality control for printed pediatric orodispersible drug delivery systems containing propranolol hydrochloride.: This article discusses the use of a colorimetric method to ensure quality control in 3D printed pediatric drug delivery systems, incorporating saccharin sodium salt hydrate as a sweetener, emphasizing its role in improving the taste and compliance of pediatric medications (Vakili et al., 2016).

Azioni biochim/fisiol

′First generation′ synthetic sugar alternative that has been studied for its carcinogenic potential.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number

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Sodium Cyclamate analytical standard

Supelco

47827

Sodium Cyclamate

Saccharin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1341

Saccharin

Saccharin for synthesis

Sigma-Aldrich

8.20128

Saccharin

Neotame analytical standard

Supelco

49777

Neotame

3,5-Dinitrobenzoic acid 99%

Sigma-Aldrich

121258

3,5-Dinitrobenzoic acid

Acesulfame K for food analysis, ≥99.0%

Supelco

04054

Acesulfame K

Denatonium benzoate ≥98%

Sigma-Aldrich

D5765

Denatonium benzoate

Butyl 4-hydroxybenzoate ≥99.0% (GC)

Sigma-Aldrich

54680

Butyl 4-hydroxybenzoate

Chloroacetic anhydride 95%

Sigma-Aldrich

215163

Chloroacetic anhydride

Robert A Boakes et al.
Physiology & behavior, 218, 112822-112822 (2020-02-01)
Rats first given 24-h access to 10% sucrose for 4 or 12 days (Stage 1) were then switched to a saccharin solution for a 12-day Stage 2. The initial result of this switch was that these Sucrose groups drank less
Simone Rehn et al.
Physiology & behavior, 207, 15-27 (2019-05-06)
When animals are given access to a palatable food or drink on some days but not on others, the amount they consume can far exceed the daily amounts consumed by controls given daily access. A previous study demonstrated such bingeing
Valentina Sabino et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(6), 1482-1493 (2008-10-24)
Sigma-Receptors (SigRs) have been implicated in behavioral and appetitive effects of psychostimulants and may also modulate the motivating properties of ethanol. This study tested the hypothesis that SigRs modulate ethanol reinforcement and contribute to excessive ethanol intake. The effects of
Deirdre M McCarthy et al.
Scientific reports, 10(1), 11974-11974 (2020-07-21)
The use of non-nutritive sweeteners such as saccharin is widely prevalent. Although saccharin is considered safe for human consumption, it produces behavioral changes in experimental animals. We report that saccharin's behavioral effects are much more pervasive than currently recognized. In
Rhian Alice Ceredig et al.
Frontiers in molecular neuroscience, 12, 324-324 (2020-03-03)
Neuropathic pain is a challenging condition for which current therapies often remain unsatisfactory. Chronic administration of β2 adrenergic agonists, including formoterol currently used to treat asthma and chronic obstructive pulmonary disease, alleviates mechanical allodynia in the sciatic nerve cuff model
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