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P4562

Sigma-Aldrich

Sodium pyruvate

powder, BioXtra, suitable for mouse embryo cell culture

Sinonimo/i:

α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt

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About This Item

Formula condensata:
CH3COCOONa
Numero CAS:
Peso molecolare:
110.04
Beilstein:
3568341
Numero CE:
Numero MDL:
Codice UNSPSC:
12352207
ID PubChem:
NACRES:
NA.75

Nome Commerciale

BioXtra

Livello qualitativo

Saggio

≥99%

Stato

powder

tecniche

cell culture | embryo: suitable

Punto di fusione

>300 °C (lit.)

Solubilità

H2O: 100 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
DAEPDZWVDSPTHF-UHFFFAOYSA-M

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Descrizione generale

Pyruvate, the end-product of the glycolysis pathway, is the anion of pyruvic acid.

Applicazioni

Sodium pyruvate has been used:
  • as a supplement in Ca2+ + N-Tris(hydroxymethil)methyl-2-aminoethanesulfonic acid (TES)–NaCl medium for sperm incubation
  • as a supplement in TCM-199 hepes modification solution for cumulus-oocytes complexes (COC′s) culture
  • as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture mouse primary hepatocytes (MPHs) and also to intraperitoneally inject fasted mice for glucose production assessment

Azioni biochim/fisiol

Sodium pyruvate is mainly used as a constituent in culture broth and media. It exhibits anti-oxidation and anti-inflammatory properties. Hence sodium pyruvate is considered a possible therapy for allergic rhinitis. Sodium pyruvate might also be a new approach treating lactic acidosis.
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted at 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Sens. 1B

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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