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P2906

Sigma-Aldrich

Poli(etilenglicole)

Hybri-Max™, mol wt 3,000-3,700, waxy solid, BioReagent, suitable for hybridoma

Sinonimo/i:

PEG

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About This Item

Formula condensata:
H(OCH2CH2)nOH
Numero CAS:
25322-68-3
Numero MDL:
MFCD00081839
Codice UNSPSC:
12161902
ID PubChem:
24898372
NACRES:
NA.75

Origine biologica

synthetic (organic)

Livello qualitativo

200

Grado

Hybri-Max™

Sterilità

autoclaved

Nome Commerciale

BioReagent

Forma fisica

waxy solid

PM

3,000-3,700

tecniche

cell culture | hybridoma: suitable

Impurezze

endotoxin, tested

Stringa SMILE

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descrizione generale

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It either exists in the form of a linear or branched structure. It aids in the purification and crystal growth of proteins and nucleic acids. PEG along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials. It permits cell fusion through its interaction with the cell membrane.

Applicazioni

Poly(ethylene glycol) has been used in the production of monoclonal antibodies.
Recommended for cell fusion.

Note legali

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

281.5 °F - closed cup

Punto d’infiammabilità (°C)

138.6 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Poli(etilenglicole) United States Pharmacopeia (USP) Reference Standard

USP

1546547

Poli(etilenglicole)

Poli(etilenglicole) average mol wt 1,450

Sigma-Aldrich

P5402

Poli(etilenglicole)

Polyethylene glycol solution BioUltra, for molecular biology, 1,000, ~50% in H2O

Sigma-Aldrich

76293

Polyethylene glycol solution

Poli(etilenglicole) BioUltra, 4,000

Sigma-Aldrich

95904

Poli(etilenglicole)

Poli(etilenglicole) Mr ~1500, pkg of 10 × 4 mL, solution

Roche

10783641001

Poli(etilenglicole)

Poli(etilenglicole) BioUltra, 1,500

Sigma-Aldrich

86101

Poli(etilenglicole)

Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody
Yu S, et al.
Neuroscience journal, 145(2), 539-555 (2007)
Harris JM
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Agathe Dubuisson et al.
Cell death & disease, 10(2), 101-101 (2019-02-06)
Development of therapeutic antibodies in oncology has attracted much interest in the past decades. More than 30 of them have been approved and are being used to treat patients suffering from cancer. Despite encouraging results, and albeit most clinical trials
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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