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Key Documents

N8159

Sigma-Aldrich

Albumin, Nitrated from bovine serum

lyophilized powder

Sinonimo/i:

Nitrated BSA

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.41

Origine biologica

bovine

Livello qualitativo

Forma fisica

lyophilized powder

tecniche

immunoblotting: suitable

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

bovine ... ALB(280717)

Categorie correlate

Descrizione generale

Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.

Applicazioni

Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).

Azioni biochim/fisiol

Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.

Stato fisico

Lyophilized from 0.01 M phosphate buffered saline, pH 7.4

Nota sulla preparazione

Bovine serum albumin (BSA) nitrated with peroxynitrite.

Risultati analitici

Does not contain sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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