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Key Documents

Altri documenti

N7627

Sigma-Aldrich

L-Norvaline

arginase inhibitor

Sinonimo/i:

(S)-(+)-2-Aminopentanoic acid, (S)-2-Aminovaleric acid

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About This Item

Formula condensata:
CH3CH2CH2CH(NH2)CO2H
Numero CAS:
6600-40-4
Peso molecolare:
117.15
Beilstein:
1721162
Numero CE:
229-543-3
Numero MDL:
MFCD00064421
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
24897833
NACRES:
NA.26

Livello qualitativo

200

Saggio

≥99% (TLC)

Forma fisica

powder

Colore

white

Punto di fusione

>300 °C (lit.)

applicazioni

detection

Stringa SMILE

CCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
SNDPXSYFESPGGJ-BYPYZUCNSA-N

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Categorie correlate

Applicazioni


  • Nanodrugs mediate TAMs-related arginine metabolism interference to boost photodynamic immunotherapy.: This study explores the use of nanodrugs to interfere with arginine metabolism in tumor-associated macrophages (TAMs), enhancing the efficacy of photodynamic immunotherapy. L-Norvaline plays a crucial role in this metabolic interference (Chen et al., 2024).

Azioni biochim/fisiol

L-Norvaline enhances NO production from activated macrophages.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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L-Norvaline-1-13C 99 atom % 13C

Sigma-Aldrich

570117

L-Norvaline-1-13C

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Sigma-Aldrich

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L-Norleucine

L-2-Aminobutyric acid ≥99% (titration)

Sigma-Aldrich

A1879

L-2-Aminobutyric acid

Sarcosine BioXtra

Sigma-Aldrich

S7672

Sarcosine

Sarcosine 98%

Sigma-Aldrich

131776

Sarcosine

Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
W Sosroseno et al.
Oral microbiology and immunology, 21(3), 145-150 (2006-04-22)
The aim of the present study was to determine whether or not lipopolysaccharide from Actinobacillus actinomycetemcomitans could stimulate arginase activity in a murine macrophage cell line (RAW264.7 cells). RAW264.7 cells were treated with A. actinomycetemcomitans-lipopolysaccharide or lipopolysaccharide from Escherichia coli
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