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N6877

Sigma-Aldrich

L-Norleucine

≥98% (TLC)

Sinonimo/i:

(S)-(+)-2-Aminohexanoic acid, (S)-2-Aminocaproic acid

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About This Item

Formula condensata:
CH3(CH2)3CH(NH2)CO2H
Numero CAS:
327-57-1
Peso molecolare:
131.17
Beilstein:
1721750
Numero CE:
206-321-4
Numero MDL:
MFCD00064423
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
24897796
NACRES:
NA.26

Livello qualitativo

200

Saggio

≥98% (TLC)

Forma fisica

powder

Colore

white

Punto di fusione

>300 °C (lit.)

applicazioni

detection

Stringa SMILE

CCCC[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
LRQKBLKVPFOOQJ-YFKPBYRVSA-N

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Applicazioni


  • l-norleucine on high glucose-induced insulin sensitivity and mitochondrial function in skeletal muscle cells. This study explores the beneficial effects of L-Norleucine on insulin sensitivity and mitochondrial function, underlining its potential in metabolic pathway research and its application in managing diabetes through targeted amino acid therapy (Ding et al., 2024).

Azioni biochim/fisiol

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Altre note

Non-essential amino acid.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Classi di pericolo

Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

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Following the studies of urea denaturation of β-hairpins using molecular dynamics, in this paper, molecular dynamics simulations of two peptides, a 35 residue three helix bundle villin headpiece protein HP-35 and its doubly norleucine-substituent mutant (Lys24Nle/Lys29Nle) HP-35 NleNle, were undertaken
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