L9017
Lectin from Phaseolus vulgaris (red kidney bean)
Phytohemagglutinin PHA-P, BioXtra, purified by affinity chromatography, lyophilized powder
Sinonimo/i:
Phaseolus vulgaris agglutinin, PHA
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Prodotti consigliati
Origine biologica
Phaseolus vulgaris
Nome Commerciale
BioXtra
Forma fisica
lyophilized powder
Potenza
≤17 μg per mL agglutination activity
Purificato mediante
affinity chromatography
Impurezze
salt, essentially free
Temperatura di conservazione
2-8°C
Cerchi prodotti simili? Visita Guida al confronto tra prodotti
Descrizione generale
Lectins are carbohydrate-binding proteins, that contains four subunits with a molecular weight of 125 kDa. Leucoagglutinin PHA-L is a plant lectin, which is transported by the neurons in the central nervous system.
Applicazioni
Lectin from Phaseolus vulgaris (red kidney bean) has been used:
- for phytohemagglutinin (PHA) swelling assay
- for lymphocyte activation assay
- to evaluate cell-mediated immune response
Azioni biochim/fisiol
Lectin agglutinates cells and precipitates polysaccharides and glycoproteins. It has anti-cancer, anti-human immunodeficiency virus (anti-HIV) and anti-microbial infection properties. Lectin is associated with toxic allergens and hemagglutinins. Lectin inhibits mucosal atrophy, lowers type 2 diabetes and obesity, enhances nutrient absorption and regulates drug targeting.
PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.
PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides. PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin. PHA-M is the mucoprotein form. Conjugates are prepared from the corresponding purified lectins.
PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides. PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin. PHA-M is the mucoprotein form. Conjugates are prepared from the corresponding purified lectins.
Qualità
Mitogenic activity at ≤10 μg per mL.
Risultati analitici
Agglutination activity is expressed in mg/mL and is determined from serial dilutions of a 1 mg/mL solution. This activity is the lowest concentration to agglutinate a suspension of 2% human erythrocytes in phosphate buffered saline, pH 6.8 after 1 hr incubation at 25 °C. Mitogenic activity is determined by BrdU incorporation.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
The Lectins: Properties, Functions, and Applications in Biology and Medicine (2012)
Chickadees faced with unpredictable food increase fat reserves but certain components of their immune function decline
Cornelius EA, et al.
Physiological and Biochemical Zoology : Pbz, 90(2), 190-200 (2017)
Effect of propolis and zinc methionine supplementation on improvement of productive, reproductive and immunity performance of local developed in sash strain under egyptian summer conditions.
Habeib AA, et al.
Egyptian Poultry Science Journal, 39(1), 253-273 (2019)
Second case of HOIP deficiency expands clinical features and defines inflammatory transcriptome regulated by LUBAC
Oda H, et al.
Frontiers in Immunology, 10, 479-479 (2019)
Jon S Beadell et al.
PloS one, 2(9), e896-e896 (2007-09-20)
Dramatic declines of native Hawaiian avifauna due to the human-mediated emergence of avian malaria and pox prompted an examination of whether island taxa share a common altered immunological signature, potentially driven by reduced genetic diversity and reduced exposure to parasites.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.