L4516
Lipopolysaccharides from Escherichia coli O127:B8
BioXtra, suitable for cell culture, γ-irradiated
Sinonimo/i:
LPS
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About This Item
Prodotti consigliati
Origine biologica
Escherichia coli (O127:B8)
Livello qualitativo
Sterilità
γ-irradiated
Nome Commerciale
BioXtra
Forma fisica
lyophilized powder
Purificato mediante
gel-filtration chromatography
tecniche
cell culture | mammalian: suitable
Impurezze
<1% Protein (Lowry)
Solubilità
H2O: 5 mg/mL, slightly hazy
Temperatura di conservazione
2-8°C
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Applicazioni
Lipopolysaccharides from Escherichia coli 0127:B8 has been used:
- to study the LPS-induced macrophage survival in mice
- to elicit the secretion of cytokines by cattle PBMC
- to study apoptosis of highly susceptible macrophage cells in a LPS-induced proinflammatory environment
- to perform autophagy assay in BV2 and BV2-LC3 cells
- for stimulation of human monocytes, macrophages and mouse microglia cells
- to induce pentraxin-3 expression in 293T cells
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Azioni biochim/fisiol
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4). Being an immunogenic antigen, it enhances immune responses to soluble antigens.
Ricostituzione
Lipopolysaccharides are supplied as lyophilized, γ-irradiated powders. To reconstitute, add 1 ml sterile balanced salt solution or tissue culture medium to the vial (1 mg) and gently swirl until the powder dissolves. Reconstituted product may be further diluted to desired working concentrations using sterile balanced salt solution or tissue culture medium.
Altre note
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 2 Oral
Codice della classe di stoccaggio
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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