Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

I8885

Sigma-Aldrich

Anti-Human IgG (Fc specific) antibody produced in goat

whole antiserum

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

goat

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

whole antiserum

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

contiene

15 mM sodium azide

tecniche

indirect ELISA: 1:50,000
quantitative precipitin assay: 4.0-7.0 mg/mL

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

Specificità

Specificity for the Fc fragment of human IgG is determined by immunoelectrophoresis (IEP) versus normal human serum and Fc fragment of human IgG. No reactivity is observed versus purified human IgA, IgG (Fab fragment), IgM, Bence Jones kappa and Bence Jones lambda myeloma proteins.

Applicazioni

Anti-Human IgG (Fc specific) antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA).

Azioni biochim/fisiol

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Stato fisico

Goat Anti-Human IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as a preservative.

Stoccaggio e stabilità

For continuous use, store at 2-8°C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. This goat antiserum was maintained at pH 5.0 for 40 minutes to meet U.S.D.A. requirements.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

<BIG><BIG>Nezlin R</BIG></BIG>
The Immunoglobulins: Structure and Function (1998)
Specific IgG for cat allergens in patients with allergic conjunctivitis
<BIG><BIG>Miyama A, et al</BIG></BIG>
International Ophthalmology, 35, 575-586 (2015)
<BIG><BIG>Calabi F and Neuberger MS</BIG></BIG>
Molecular Genetics of Immunoglobulin, 17 (1987)
Thomas McDonnell et al.
Frontiers in immunology, 9, 2244-2244 (2018-10-17)
Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome (APS), are a heterogeneous group of autoantibodies raised against circulating blood proteins. Of these proteins, the phospholipid-binding b2-glycoprotein I (β2GPI) is considered to be the main autoantigen in APS. Indeed, IgG
Julie Ducreux et al.
Bioconjugate chemistry, 19(10), 2088-2094 (2008-09-24)
PEGylation of antibodies is known to increase their half-life in systemic circulation, but nothing is known regarding whether PEGylation can improve the inhibitory potency of antibodies against target receptors. In this paper, we have examined this question using antibodies directed

Articoli

Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.