Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

I2386

Sigma-Aldrich

Anti-Human IgM (μ-chain specific) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-IgM produced in Goat, Goat Anti-Human IgM, IgM Detection Antibody

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Numero MDL:
MFCD00162459
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

goat

Livello qualitativo

300

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

tecniche

indirect ELISA: 1:20,000-1:40,000

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.

Applicazioni

Anti-Human IgM (μ-chain specific) antibody produced in goat has been used in enzyme linked immunosorbent assay (ELISA).

Azioni biochim/fisiol

Immunoglobulin M (IgM) antibodies are the primary ones to be produced in response to antigen. They bind with low affinity but exhibit a broad specificity to a variety of antigens. IgM constitutes 15% of adult immunoglobulins. IgM is important for fetal and neonatal host defenses for several reasons. IgM molecule efficiently activates classical pathway of complement. Its pentameric structure helps in accomodating multivalent ligand binding. IgM has a prominent role in clearance of invading microorganisms from serum.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
118M4782V
108M4816V
107M4791V
116M4874V
125M4808V

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Juha Ollila et al.
Molecular immunology, 44(14), 3537-3551 (2007-05-09)
B-cell development into antibody producing cells is a complex process that relies on the tightly controlled production of hundreds of genes and proteins. A B-cell is activated through the B-cell receptor (BCR) and this activation is modified by different co-stimulatory
Avery's Diseases of the Newborn E-Book, 460-460 (2011)
Anti-protein immunoglobulin M responses to pneumococcus are not associated with aging
German EL, et al.
Pneumonia (Nathan Qld.), 10(1), 5-5 (2018)
X Guo et al.
Oncogene, 36(29), 4224-4232 (2017-04-04)
Diffuse large B-cell lymphoma (DLBCL) has been categorized into two molecular subtypes that have prognostic significance, namely germinal center B-cell like (GCB) and activated B-cell like (ABC). Although ABC-DLBCL has been associated with NF-κB activation, the relationships between activation of
J Ollila et al.
Genes and immunity, 4(5), 343-350 (2003-07-09)
The development of adaptive immunity and responses to foreign molecules and organisms relies on the highly regulated production of hundreds of proteins. B-cell maturation, from committed progenitors to terminally differentiated plasma cells, is a multistep process that requires the ordered
Visualizza tutti i documenti correlati

Articoli

Anti-Human Antibodies for COVID-19 (SARS-CoV-2) Immunoglobulin Detection Research

Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.