H135
5-Hydroxydecanoic acid sodium salt
≥97% (HPLC)
Sinonimo/i:
5-hydroxydecanoate sodium salt
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About This Item
Prodotti consigliati
Livello qualitativo
Saggio
≥97% (HPLC)
Stato
powder
Condizioni di stoccaggio
desiccated
Colore
white to beige
Solubilità
H2O: 10 mg/mL, clear
Stringa SMILE
[Na+].CCCCCC(O)CCCC([O-])=O
InChI
1S/C10H20O3.Na/c1-2-3-4-6-9(11)7-5-8-10(12)13;/h9,11H,2-8H2,1H3,(H,12,13);/q;+1/p-1
YNAGNECWEKMWRM-UHFFFAOYSA-M
Azioni biochim/fisiol
Blocks post-ischemic actions of the K+ channel activator cromakalim.
Caratteristiche e vantaggi
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Avvertenza
Hygroscopic
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Cardiology, 123(3), 177-180 (2012-11-07)
We investigated whether ischemic preconditioning (IPC) protects the right ventricular (RV) myocardium against ischemic injury in hearts treated with the specific mitochondrial ATP-sensitive potassium (K(ATP)) channel blocker 5-hydroxydecanoate (5-HD). Hearts from male Wistar rats (300 g, n = 39) were
Ischemic preconditioning of the right ventricle: a new application for an old concept?.
Cardiology, 123(3), 175-176 (2012-11-07)
Chinese medicine, 6(1), 7-7 (2011-02-16)
Danshen-Gegen decoction (DG), a Chinese herbal formula, has been demonstrated to be effective for the treatment of coronary heart disease such as myocardial infarction. In the present study, we investigated the effect of DG post-conditioning on isoproterenol (ISO)-induced myocardial injury
Pharmacology, 90(1-2), 110-116 (2012-07-21)
Eribis peptide 94 (EP 94) is a new enkephalin derivative which potently binds to the µ- and δ-opioid receptor. In this study, we determined the effects of EP 94 and potential mechanism(s) involved in cardioprotection of the rat heart. An
Ischemia reperfusion injury, KATP channels, and exercise-induced cardioprotection against apoptosis.
Journal of applied physiology (Bethesda, Md. : 1985), 113(3), 498-506 (2012-06-02)
Exercise is a potent stimulus against cardiac ischemia reperfusion (IR) injury, although the protective mechanisms are not completely understood. The study purpose was to examine whether the mitochondrial or sarcolemmal ATP-sensitive potassium channel (mito K(ATP) or sarc K(ATP), respectively) mediates
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