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Key Documents

Altri documenti

F9381

Sigma-Aldrich

Fluorometholone

≥98%

Sinonimo/i:

11β,17α-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione

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About This Item

Formula empirica (notazione di Hill):
C22H29FO4
Numero CAS:
426-13-1
Peso molecolare:
376.46
Numero CE:
207-041-5
Numero MDL:
MFCD00056461
Codice UNSPSC:
12352212
ID PubChem:
24894996
NACRES:
NA.77

Saggio

≥98%

Stringa SMILE

C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
FAOZLTXFLGPHNG-KNAQIMQKSA-N

Informazioni sul gene

human ... NR3C1(2908)

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Categorie correlate

Applicazioni


  • Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears.: This research explores the changes in tear protein expression due to topical fluorometholone and environmental stress, offering insights into ocular surface inflammatory responses (Nättinen et al., 2018).

  • General Pharmacokinetic Model for Topically Administered Ocular Drug Dosage Forms.: This study provides a pharmacokinetic model applicable to topical ocular medications, including fluorometholone, enhancing understanding of drug dynamics in eye treatments (Deng et al., 2016).

Azioni biochim/fisiol

Clinically significant in allergic conjunctivitis and as anti-inflammatory following cataract surgery.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302 + H312 + H332

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

N6250

1,3-Dihydroxynaphthalene

Florfenicol analytical standard, for drug analysis

Supelco

F1427

Florfenicol

1-clorobutano anhydrous, 99.5%

Sigma-Aldrich

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1-clorobutano

Folic acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

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Prednisolone ≥99%

Sigma-Aldrich

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Hydrocortisone ≥98% (HPLC)

Sigma-Aldrich

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Hydrocortisone

N-Nitrosodimethylamine (NDMA) solution certified reference material, 200 μg/mL in methanol

Supelco

48670

N-Nitrosodimethylamine (NDMA) solution

Ferric citrate BioReagent, suitable for cell culture

Sigma-Aldrich

F3388

Ferric citrate

Kaevalin Lekhanont et al.
Cornea, 31(2), 155-161 (2011-11-15)
To investigate the efficacy and safety of subconjunctival bevacizumab injection for the treatment of impending recurrent pterygium. A prospective, randomized, single-masked, controlled trial was conducted in 80 patients with impending recurrent pterygium. Patients were randomized into 4 groups using random
Alejandro Portero et al.
Cornea, 32(2), 161-164 (2012-06-08)
Hairs from the caterpillar of the pine processionary moth, Thaumetopoea pityocampa, located in the pine forests of southern Europe and elsewhere, can become embedded in the cornea and conjunctiva. Disorders produced by the urticating hairs can be classified into a
Brett W Davies et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 129(7), 909-913 (2011-07-13)
To compare topical interleukin 1 receptor antagonist (IL-1ra) to steroid treatment following photorefractive keratectomy (PRK) in rabbit eyes. Our study is a randomized, investigator-masked study that was approved by the Institutional Animal Care and Use Committee. Following standard PRK, 48
Deniz Hos et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 129(4), 445-452 (2011-04-13)
To analyze whether topical application of corticosteroids inhibits inflammatory corneal lymphangiogenesis and to study the potential underlying antilymphangiogenic mechanisms. Inflammatory corneal neovascularization was induced by suture placement, and the corneas were then treated with topical fluorometholone, prednisolone acetate, or dexamethasone
Lei Zhu et al.
Molecular vision, 18, 1803-1812 (2012-07-21)
To evaluate the effect of the topical steroid, fluorometholone, and the non-steroidal anti-inflammatory drugs (NSAIDs), nepafenac and ketorolac, on inflammatory cytokine expression of the ocular surface in the botulium toxin B-induced murine dry eye model. Topical artificial tears (0.5% carboxymethylcellulose
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