D2625

Dansyl chloride

BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)

• Sinonimo/i: 5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
• Formula empirica (notazione di Hill): C₁₂H₁₂ClNO₂S
• Numero CAS: 605-65-2
• Peso molecolare: 269.75
• Beilstein: 2217205
• Numero CE: 210-092-6
• Numero MDL: MFCD00003985
• Codice UNSPSC: 12352101
• ID PubChem: 24893700
• NACRES: NA.26

Proprietà

• Nome Commerciale: BioReagent
• Livello qualitativo: 200
• Saggio: ≥99% (HPLC)
• Forma fisica: powder and chunks
• Colore: yellow to yellow-orange
• Punto di fusione: 72-74 °C (lit.)
• Solubilità: acetone: 20 mg/mL
• Compatibilità: suitable for amino acid labeling
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
• InChI: 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3; XPDXVDYUQZHFPV-UHFFFAOYSA-N

Descrizione

Applicazioni

Dansyl chloride has been used:

• as a fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase high performance liquid chromatography (HPLC)
• in the derivatization of plasma samples
• in the quantification of immobilized alkaline phosphatase

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

Azioni biochim/fisiol

Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.

Informazioni sulla sicurezza

• Pittogrammi: GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H290,H314
• Consigli di prudenza: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges