A2691
Anti-Human IgA (α-chain specific)−Agarose antibody produced in goat
affinity isolated antibody, adsorbed with mouse and rat IgG
Sinonimo/i:
Goat Anti-Human IgA
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About This Item
Prodotti consigliati
Origine biologica
goat
Livello qualitativo
Coniugato
agarose conjugate
Forma dell’anticorpo
affinity isolated antibody
Tipo di anticorpo
secondary antibodies
Clone
polyclonal
Stato
PBS suspension
Reattività contro le specie
human
Non deve reagire con
rat, mouse
Capacità
3-4 mg/mL binding capacity (human IgA)
Temperatura di conservazione
2-8°C
modifica post-traduzionali bersaglio
unmodified
Descrizione generale
Binding Capacity: One mL of antibody binds 3-4 mg human IgA. Elution Capacity is 2-4 mg/mL.
IgA antibody plays an essential role in mucosal immunity. It has shown to bind immunogens/pathogens to restrict them from entering the mucosal membrane. The Anti-Human IgA (α-chain specific) product increases sensitivity to human IgA without cross-reactivity to other substances. Offering minimal interspecies cross reactivity to mouse or a rat, making it ideal for use in screening antibodies produced by a hybridoma cells containing a mouse or a rat immunoglobulins.
Immunogeno
IgA produced from transformed cell line of human Epstein-Barr virus.
Applicazioni
Affinity chromatography using anti-human IgA antibody linked to agarose was performed to purify proteins from 2E9IgA1 transfectant cells.
Anti-Human IgA (α-chain specific)-Agarose antibody produced in goat has been used in affinity chromatography and quantitative enzyme linked immunosorbent assay (ELISA).
Stato fisico
Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Susanne Wolbank et al.
Journal of virology, 77(7), 4095-4103 (2003-03-14)
We have previously generated human monoclonal anti-human immunodeficiency virus type 1 (anti-HIV-1) antibodies 2F5IgG and 2G12IgG with an exceptional cross-clade neutralizing potential. 2F5IgG and 2G12IgG passively administrated to macaques were able to confer complete protection from both intravenous and mucosal
Poor ex vivo induction of T-cell responses to idiotype or tumor cell lysate-pulsed autologous dendritic cells in advanced pre-treated multiple myeloma
Garderet L, et al.
Leukemia & Lymphoma, 47(7), 1340-1347 (2006)
Suckow MA, et al.
The Laboratory Rat (2005)
Y J Wen et al.
Blood, 97(6), 1750-1755 (2001-03-10)
Multiple myeloma (MM) is a B-cell malignancy. The monoclonal immunoglobulin, secreted by myeloma plasma cells, carries unique antigenic determinants (idiotype [Id]) that can be regarded as a tumor-specific antigen. Id-based immunotherapy has been explored in myeloma patients for the purpose
J Berdoz et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(6), 3029-3034 (1999-03-17)
The hallmark of a mucosal immune response is the production of antigen-specific secretory IgA (S-IgA) antibodies in external secretions. S-IgA consists of ten polypeptides produced in two different cell lineages. The heavy and light chains in plasma cells assemble into
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
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