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78544

Sigma-Aldrich

Glucose tetrasaccharide

≥99.0% (TLC)

Sinonimo/i:

Glcα1-6Glcα1-4Glcα1-4Glc

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About This Item

Formula empirica (notazione di Hill):
C24H42O21
Numero CAS:
35175-16-7
Peso molecolare:
666.58
Numero MDL:
MFCD09840666
Codice UNSPSC:
12352201
ID PubChem:
329768157
NACRES:
NA.28

Saggio

≥99.0% (TLC)

Forma fisica

powder

Colore

white

Compatibilità

corresponds for LC-MS

Temperatura di conservazione

room temp

Stringa SMILE

OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)C(O)O[C@@H]4CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-10(29)12(31)17(36)23(43-8)45-20-7(3-27)42-24(18(37)14(20)33)44-19-6(2-26)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21?,22+,23-,24-/m1/s1
FPBCRLIOSBQLHS-QVTSYAGHSA-N

Applicazioni

Glucose tetrasaccharide (Glc4) is used as a reference in analysis of urinary glucose tetrasacchaide, a biomarker for Pompe disease and other glycogen storage diseases.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Yoav H Messinger et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 14(1), 135-142 (2012-01-13)
Infantile Pompe disease resulting from a deficiency of lysosomal acid α-glucosidase (GAA) requires enzyme replacement therapy (ERT) with recombinant human GAA (rhGAA). Cross-reactive immunologic material negative (CRIM-negative) Pompe patients develop high-titer antibody to the rhGAA and do poorly. We describe
Victoria Manwaring et al.
Journal of inherited metabolic disease, 35(2), 311-316 (2011-06-21)
A high performance liquid chromatography method, adapted from an established urinary sugars method, has been developed for the analysis of a tetraglucose oligomer (Glc(4)) in urine. Pompe disease results from defects in the activity of lysosomal acid α-glucosidase (GAA) with
Zoheb B Kazi et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 21(4), 887-895 (2018-09-15)
To investigate immune tolerance induction with transient low-dose methotrexate (TLD-MTX) initiated with recombinant human acid α-glucosidase (rhGAA), in treatment-naïve cross-reactive immunologic material (CRIM)-positive infantile-onset Pompe disease (IOPD) patients. Newly diagnosed IOPD patients received subcutaneous or oral 0.4 mg/kg TLD-MTX for 3
Johannes Brettschneider et al.
Journal of neuroimmunology, 217(1-2), 95-101 (2009-11-03)
The serum level of IgM antibodies against Glc(alpha1,4)Glc(alpha) (GAGA4) is higher in relapsing remitting multiple sclerosis (RRMS) compared to other neurological disease (OND) patients and healthy controls (HC). Detecting the level of anti-GAGA4 antibody by enzyme immunoassay and total IgM
Mikael Schwarz et al.
Journal of the neurological sciences, 244(1-2), 59-68 (2006-02-17)
There is an unmet need to develop specific biomarkers for multiple sclerosis (MS) to aid in the diagnosis, improve the management of patients and the monitoring of the effectiveness of treatment. We have screened serum from patients with relapsing-remitting MS
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