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78264

Sigma-Aldrich

7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin

BioReagent, suitable for fluorescence, ≥85% (HPLC)

Sinonimo/i:

DCIA

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About This Item

Formula empirica (notazione di Hill):
C22H23IN2O3
Numero CAS:
76877-34-4
Peso molecolare:
490.33
Numero MDL:
MFCD00467581
Codice UNSPSC:
12352200
ID PubChem:
329768132
NACRES:
NA.31

Nome Commerciale

BioReagent

Saggio

≥85% (HPLC)

Forma fisica

crystals

Fluorescenza

λex 389 nm; λem 467 nm in methanol

Compatibilità

suitable for fluorescence

Stringa SMILE

CCN(CC)c1ccc2C(C)=C(C(=O)Oc2c1)c3ccc(NC(=O)CI)cc3

InChI

1S/C22H23IN2O3/c1-4-25(5-2)17-10-11-18-14(3)21(22(27)28-19(18)12-17)15-6-8-16(9-7-15)24-20(26)13-23/h6-12H,4-5,13H2,1-3H3,(H,24,26)
WIXAQXKQLNRFDF-UHFFFAOYSA-N

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301,H413

Consigli di prudenza

P273 - P301 + P310 + P330

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Chronic 4

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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I D Clark et al.
Analytical biochemistry, 213(2), 296-302 (1993-09-01)
In this study a Ca(2+)-binding 14mer peptide was synthesized with the sequence GDKNADGCIEFEEL, allowing covalent attachment of sulfhydryl-reactive fluorescent molecules at position 7 of the 12-residue, metal-binding loop (underlined). This provided the opportunity to select donor molecules with suitable spectral
Carsten Rendenbach et al.
Microsurgery, 39(4), 304-309 (2018-08-31)
Free flap surgery can be associated with donor-site morbidity. The purpose of this study was to analyze long-term functional outcomes at the donor site after deep circumflex iliac artery (DCIA) bone flap harvesting. Fourteen patients (8 men and 6 women
T O Sippel
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 29(2), 314-316 (1981-02-01)
N-(4-(7 - Diethylamino - methylcoumarin - 3 yl)phenyl)maleimide (CPM) and the corresponding iodoacetamide are described. When applied to sections at pH 6 and 9, respectively, the two fluorogens are very similar in their reactivity and selectivity toward thiols with which
W D Picking et al.
Biochemistry, 31(8), 2368-2375 (1992-03-03)
The fate of the amino termini of nascent polyalanine, polyserine, and polylysine was monitored by fluorescence techniques as each was translated on Escherichia coli ribosomes. A coumarin probe was placed at the alpha-amino group of a synthetic elongator alanyl-tRNA or
Mélodie Duval et al.
Methods (San Diego, Calif.), 117, 48-58 (2016-12-29)
RNA-protein interactions are at the bases of many biological processes, forming either tight and stable functional ribonucleoprotein (RNP) complexes (i.e. the ribosome) or transitory ones, such as the complexes involving RNA chaperone proteins. To localize the sites where a protein
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