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Merck
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Documenti fondamentali

74667

Sigma-Aldrich

Nourseothricin sulfate

≥85% (HPLC)

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
51102829
NACRES:
NA.85

Origine biologica

Streptomyces noursei

Livello qualitativo

Saggio

≥85% (HPLC)

Stato

solid

Colore

white to light brown

Solubilità

H2O: soluble 200 mg/mL

Compatibilità

suitable for (selection agent for molecular genetic research work)

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria
fungi
mycobacteria
mycoplasma
parasites
viruses
yeast

Modalità d’azione

protein synthesis | interferes

Temperatura di conservazione

2-8°C

Descrizione generale

Chemical structure: peptidyl nucleoside

Applicazioni

Noursethricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.

Azioni biochim/fisiol

Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.

Confezionamento

10mg, 100mg

Altre note

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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