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Merck
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61251

Sigma-Aldrich

Palmitoyl-L-carnitine

≥97.0% (HPLC)

Sinonimo/i:

(2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium inner salt, L-Carnitine hexadecanoyl ester, C16-Carnitine, Hexadecanoyl-L-carnitine

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About This Item

Formula empirica (notazione di Hill):
C23H45NO4
Numero CAS:
2364-67-2
Peso molecolare:
399.61
Beilstein:
4152034
Codice UNSPSC:
12352211
ID PubChem:
329759410
NACRES:
NA.26

Livello qualitativo

100

Saggio

≥97.0% (HPLC)

Attività ottica

[α]/D -17±2°, c = 1 in methanol

Impurezze

≤10% water

Temperatura di conservazione

2-8°C

Stringa SMILE

C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O

InChI

1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m1/s1
XOMRRQXKHMYMOC-OAQYLSRUSA-N

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Azioni biochim/fisiol

L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Margaret-Ann M Nelson et al.
Amino acids, 51(1), 97-102 (2018-09-08)
Oxidative deamination of norepinephrine (NE) and dopamine (DA) by monoamine oxidase (MAO) generates the catecholaldehydes 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL) and 3,4-dihydroxyphenylacetaldehyde (DOPAL), respectively, and H2O2. Catecholaldehydes are highly reactive electrophiles that have been implicated as causal factors in the etiology of neurodegenerative
Stephanie J Mihalik et al.
Obesity (Silver Spring, Md.), 18(9), 1695-1700 (2010-01-30)
Dysregulation of fatty acid oxidation (FAO) is recognized as important in the pathophysiology of obesity and insulin resistance (IR). However, demonstrating FAO defects in vivo in humans has entailed complex and invasive methodologies. Recently, the identification of genetic blocks in
Sanne J C M Frambach et al.
Biochimica et biophysica acta. Molecular basis of disease, 1866(6), 165727-165727 (2020-02-20)
Mitochondrial complex I (CI), the first multiprotein enzyme complex of the OXPHOS system, executes a major role in cellular ATP generation. Consequently, dysfunction of this complex has been linked to inherited metabolic disorders, including Leigh disease (LD), an often fatal
Katherine A Overmyer et al.
Cell metabolism, 21(3), 468-478 (2015-03-05)
Maximal exercise-associated oxidative capacity is strongly correlated with health and longevity in humans. Rats selectively bred for high running capacity (HCR) have improved metabolic health and are longer-lived than their low-capacity counterparts (LCR). Using metabolomic and proteomic profiling, we show
Sang Hoon Lee et al.
Journal of controlled release : official journal of the Controlled Release Society, 311-312, 74-84 (2019-09-06)
This research aimed to develop a pH-responsive organic-inorganic hybrid nanocomposite as an effective oral delivery system for protein drugs. Three different nanocomposites were prepared by using bovine serum albumin (BSA) as a model protein. A nanocomplex of BSA with 3-aminopropyl
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