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71778

Sigma-Aldrich

Sodium nitroprusside dihydrate

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99%

Sinonimo/i:

Nitroprusside sodium, SNP, Sodium nitroferricyanide, Sodium pentacyanonitrosylferrate

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About This Item

Formula condensata:
Na2[Fe(CN)5NO] · 2H2O
Numero CAS:
13755-38-9
Peso molecolare:
297.95
Numero CE:
238-373-9
Numero MDL:
MFCD00149192
Codice UNSPSC:
12352300
ID PubChem:
329763522
NACRES:
NB.24

Grado

ACS reagent
puriss. p.a.

agenzia

reag. Ph. Eur.
suitable for SM 4500 - NH3

Saggio

≥99%

Forma fisica

crystals or chunks

Solubilità

water: soluble(lit.)

Anioni in tracce

chloride (Cl-): ≤100 mg/kg
hexacyanoferrate(II) ([Fe(CN)6]4-): ≤200 mg/kg
hexacyanoferrate(III) ([Fe(CN)6]3-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

Cationi in tracce

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤50 mg/kg
Cu: ≤5 mg/kg
K: ≤3000 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤50 mg/kg

Stringa SMILE

O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;
OIRZWVYIQXBRFC-UHFFFAOYSA-N

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Descrizione generale

Sodium nitroprusside dihydrate (Disodium pentacyanonitrosylferrate(2-)dihydrate, SNP) molecule contains a ferrous ion in the center, which is surrounded by five cyanide groups and a nitrosyl group. Sodium nitroprusside has clinical applications. It acts as a rapid-acting vasodilator. It is also widely employed as nitric oxide (NO) donor in various experimental models. Two metastable states of sodium nitroprusside dihydrate, Na2[Fe(CN)5NO].2H2O have been identified and their geometries have been studied by X-ray diffraction.

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301

Classi di pericolo

Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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M Chiusa et al.
European journal of histochemistry : EJH, 56(2), e15-e15 (2012-06-13)
Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reactive oxygen species.
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Diffraction studies of photoexcited crystals: Metastable nitrosyl-linkage isomers of sodium nitroprusside.
Carducci MD, et al.
Journal of the American Chemical Society, 119(11), 2669-2678 (1997)
Jae Hyung Kim et al.
Journal of applied physiology (Bethesda, Md. : 1985), 107(4), 1249-1257 (2009-08-08)
There is increasing evidence that upregulation of arginase contributes to impaired endothelial function in aging. In this study, we demonstrate that arginase upregulation leads to endothelial nitric oxide synthase (eNOS) uncoupling and that in vivo chronic inhibition of arginase restores
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Nitric oxide regulates BP by binding the reduced heme iron (Fe2+) in soluble guanylyl cyclase (sGC) and relaxing vascular smooth muscle cells (SMCs). We previously showed that sGC heme iron reduction (Fe3+ → Fe2+) is modulated by cytochrome b5 reductase
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