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Key Documents

T1600000

α-Tocopherol acetate

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

DL-α-Tocopherol acetate, Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Formula empirica (notazione di Hill):
C31H52O3
Numero CAS:
Peso molecolare:
472.74
Beilstein:
97512
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Origine biologica

synthetic

Grado

pharmaceutical primary standard

agenzia

EP

Famiglia di API

tocopherol

Forma fisica

liquid

Produttore/marchio commerciale

EDQM

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Densità

0.96 g/mL at 20 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
ZAKOWWREFLAJOT-CEFNRUSXSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. α-Tocopherol acetate, a supplement of α-tocopherol, is an active form of vitamin E. This lipid-soluble antioxidant is found in whole grains, nuts, and oils. It is known to scavenge reactive oxygen species by interacting with lipids during oxidative stress.

Applicazioni

α-Tocopherol acetate may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

No data available

Punto d’infiammabilità (°C)

No data available


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ANTIOXIDANTS-Role of Antioxidant Nutrients in Defense Systems
Encyclopedia of food sciences and nutrition, 282-289 (2003)
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European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3804-3805 (2013)
Determination of eight water-and fat-soluble vitamins in multi-vitamin pharmaceutical formulations by high-performance liquid chromatography
Moreno P and Salvado V
Journal of Chromatography A, 870(1-2), 207-215 (2000)
Flow injection spectrophotometric determination of vitamin E in pharmaceuticals, milk powder and blood serum using potassium ferricyanide-Fe (III) detection system
Jadoon S, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 21(6), 712-715 (2010)
The role of alpha-tocopherol in plant stress tolerance
Munne-Bosch S
Journal of Plant Physiology, 162(7), 743-748 (2005)

Protocolli

Separation of Retinyl acetate, analytical standard; δ-Tocopherol, analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Retinol palmitate, analytical standard.

Separation of Retinyl acetate, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; δ-Tocopherol, analytical standard; Retinol palmitate, analytical standard

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