SMB01333

Acetyl-6-formylpterin

≥95% (HPLC)

• Sinonimo/i: 2-Acetamido-4-oxopteridine-6-carboxaldehyde, 2-Acetamido-6-formylpteridin-4(3H)-one, 2-Acetylamino-4-hydroxy-6-formylpteridine, 2-Acetamido-6-formylpteridin-4-one, N-(6-formyl-4-hydroxy-2-pteridinyl)acetamide, N-(6-formyl-4-oxo-1H-pteridin-2-yl)acetamide
• Formula empirica (notazione di Hill): C₉H₇N₅O₃
• Numero CAS: 29769-49-1
• Peso molecolare: 233.18
• Numero MDL: MFCD28368502
• Codice UNSPSC: 12352205
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Stato: powder
• Temperatura di conservazione: −20°C
• Stringa SMILE: CC(=O)NC1=NC2=NC=C(N=C2C(=O)N1)C=O
• InChI: 1S/C9H7N5O3/c1-4(16)11-9-13-7-6(8(17)14-9)12-5(3-15)2-10-7/h2-3H,1H3,(H2,10,11,13,14,16,17); DDBCPKAHJKOGKK-UHFFFAOYSA-N

Descrizione

Descrizione generale

Acetyl-6-formylpterin is a vitamin B9 (folate) metabolite and ligand to MHC class I-related protein 1 (MR1) antigens presented on mucosal-associated invariant T (MAIT) cells.

Acetyl-6-formylpterin, also known as 2-Acetamido-6-formylpteridin-4-one, is a pteridine derivative and a reductive amination product derived from folic acid. This unique compound undergoes a reductive amination reaction, generating formyl groups that can be subsequently acetylated or alkylated, resulting in the formation of stable compounds with diverse properties. Current research highlights the multifaceted nature of this compound, indicating its potential biological activities, including neuroprotective, antitumor, and anticancer properties.

Moreover, acetyl-6-formylpterin serves as a precursor in the synthesis of 2′-hydroxy-7,8-dihydrofolate, a metabolite associated with para-aminosalicylic acid (PAS) in M. tuberculosis. This compound′s versatility and involvement in various biological processes make it an intriguing molecule for metabolomics and biochemical research.

Applicazioni

Acetyl-6-formylpterin has been used:

• to study the potential reversal of iver fibrosis
• in metabolomics research

Azioni biochim/fisiol

Acetyl-6-formylpterin is involved in the enzymatic conversion of GTP to BH4, playing a role in the regulation of neurotransmitter synthesis and other biological processes.

Caratteristiche e vantaggi

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Altre note

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable