PHR1569

L-carnitina

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: (−)-(R)-3-idrossi-4-(trimetilammonio)butirrato, Vitamina B_T
• Formula condensata: (CH₃)₃N⁺CH₂CH(OH)CH₂COO^-
• Numero CAS: 541-15-1
• Peso molecolare: 161.20
• Beilstein: 4292315
• Numero CE: 208-768-0
• Numero MDL: MFCD00038747
• Codice UNSPSC: 41116107
• ID PubChem: 329823478
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to Ph. Eur. L0399900; traceable to USP 1359903
• Famiglia di API: levocarnitine
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 1 g
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Punto di fusione: 197-212 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: C[N+](C)(C)C[C@H](O)CC([O-])=O
• InChI: 1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1; PHIQHXFUZVPYII-ZCFIWIBFSA-N

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Levocarnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria.

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Azioni biochim/fisiol

La carnitina è un′ammina quaternaria naturalmente presente nella maggior parte dei tessuti di mammifero. È presente in concentrazioni relativamente elevate nei muscoli scheletrici e nel cuore, dove è coinvolta nella regolazione del metabolismo energetico. Sposta il metabolismo del glucosio dalla glicolisi all′immagazzinamento del glicogeno e potenzia il trasporto degli acidi grassi a catena lunga nei mitocondri, dove vengono ossidati per produrre energia.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAB7787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable