P4347
Propylene Glycol
meets USP testing specifications
Sinonimo/i:
1,2-propandiolo, Propilenglicole
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About This Item
Formula condensata:
CH3CH(OH)CH2OH
Numero CAS:
Peso molecolare:
76.09
Beilstein:
1340498
Numero CE:
Numero MDL:
Codice UNSPSC:
12161700
ID PubChem:
NACRES:
NA.25
Prodotti consigliati
agenzia
USP/NF
meets USP testing specifications
Livello qualitativo
Densità del vapore
2.62 (vs air)
Tensione di vapore
0.08 mmHg ( 20 °C)
Temp. autoaccensione
779 °F
Limite di esplosione
12.5 %
Indice di rifrazione
n20/D 1.432 (lit.)
P. ebollizione
187 °C (lit.)
Punto di fusione
−60 °C (lit.)
Densità
1.036 g/mL at 25 °C (lit.)
applicazioni
general analytical
pharmaceutical (small molecule)
sample preparation
Stringa SMILE
CC(O)CO
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
DNIAPMSPPWPWGF-UHFFFAOYSA-N
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Descrizione generale
Propylene glycol, a low-molecular-weight aliphatic alcohol, holds significance as a key solvent in biological and pharmaceutical formulation research. Its outstanding miscibility with water and diverse organic compounds, coupled with its low freezing point, low vapor pressure, and non-toxic nature, positions it as a preferred choice for a variety of research applications, particularly in sensitive biological assays and pharmaceutical preparations.
Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.
The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.
Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.
The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.
Applicazioni
Propylene glycol has been used:
- for removing excess Oil Red O stain in zebrafish larvae
- in the preparation of alginate hydrogels
- for the dissolution of androstenone
- for the calibration of cone beam scanner in computed tomography
Caratteristiche e vantaggi
- Versatile and adaptable for a wide variety of laboratory and research applications
- Meets USP testing specifications
Altre note
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Prodotto comparabile
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
219.2 °F - closed cup
Punto d’infiammabilità (°C)
104 °C - closed cup
Dispositivi di protezione individuale
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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