B4380
Bromobimane
≥97% purity, powder
Sinonimo/i:
Monobromobimane
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About This Item
Formula empirica (notazione di Hill):
C10H11BrN2O2
Numero CAS:
Peso molecolare:
271.11
Beilstein:
4430959
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47
Prodotti consigliati
product name
Bromobimane, ≥97% (HPLC)
Livello qualitativo
Saggio
≥97% (HPLC)
Forma fisica
powder
Colore
yellow
Punto di fusione
161 °C
Solubilità
acetonitrile: 20 mg/mL
ε (coefficiente d’estinzione)
4.6-5.1 at 396-398 nm in H2O
applicazioni
diagnostic assay manufacturing
hematology
histology
Temperatura di conservazione
−20°C
Stringa SMILE
CC1=C(C)C(=O)N2N1C(CBr)=C(C)C2=O
InChI
1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
AHEWZZJEDQVLOP-UHFFFAOYSA-N
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Descrizione generale
Bromobimane is also known as monobromobimane. It is also a known probe for thiols and is a fluorescent reagent activated upon a photolysis reaction.
Applicazioni
Bromobimane is used for the determination of thiols by the HPLC method. It is suitable as a pre-column derivatization agent for fluorometric determination of 2,3-dimercaptopropane-1-sulfonic acid and other dithiols. Bromobimane has been used as a fluorescent label in studying oligomycin-sensitive ATPase from beef heart mitochondria.
Bromobimane has been used for the quantitative measurement of free hydrogen sulfide in vivo and in vitro. It has been used for the labeling of proteins containing thiol groups.
Bromobimane has been used for the quantitative measurement of free hydrogen sulfide in vivo and in vitro. It has been used for the labeling of proteins containing thiol groups.
Azioni biochim/fisiol
Bromobimane in solution reacts with small thiol groups (e.g., GSH) and with reactive protein thiol groups (e.g., hemoglobin). The reaction of Bromobimane with thiols is of second-order and dependent on pH and upon reacting with thiolate, it activates the water-soluble fluorescent product for detection.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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