A6848

Aztreonam

analytical standard

• Sinonimo/i: Acido [2S-[2α,3β(Z)]]-2-[[[1-(2-ammino-4-tiazolil)-2-[(2-metil-4-osso-1-solfo-3-azetidinil)ammino]-2-ossoetilidene]ammino]ossi]-2-metilpropanoico
• Formula empirica (notazione di Hill): C₁₃H₁₇N₅O₈S₂
• Numero CAS: 78110-38-0
• Peso molecolare: 435.43
• Numero CE: 278-839-9
• Numero MDL: MFCD00072145
• Codice UNSPSC: 41116107
• ID PubChem: 329770905
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Stato: powder or crystals
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: forensics and toxicology; pharmaceutical (small molecule); veterinary
• Stringa SMILE: C[C@H]1[C@H](NC(=O)\C(=N/OC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O
• InChI: 1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1; WZPBZJONDBGPKJ-VEHQQRBSSA-N

Descrizione

Descrizione generale

Aztreonam belongs to the group of monocyclic β-lactam antibiotics, isolated from Chromobacterium violaceum. It is used against gram-negative bacterial infections, such as infections of the bladder, kidneys, bone, and urinary tract. It acts by binding to the penicillin-binding protein-3 (PBP3) and inhibiting the synthesis of bacterial cell walls causing cell lysis and death.

Applicazioni

The analytical standard can be used as follows:

• Determination of aztreonam in two simulated lung fluid solutions― artificial lysosomal fluid and gamble solution by a UV spectroscopic method
• Multi-residue analysis of eight β-lactams by ultra-high performance liquid chromatography (UHPLC) combined with a photo-diode array (PDA) detector in human plasma & serum samples
• Simultaneous quantitative analysis of nine β-lactams by UHPLC along with tandem mass spectrometry (MS/MS) in human plasma samples

Altre note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)