49797
4-Butylresorcinol
analytical standard
Sinonimo/i:
4-Butyl-1,3-benzenediol
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About This Item
Formula empirica (notazione di Hill):
C10H14O2
Numero CAS:
Peso molecolare:
166.22
Beilstein:
1942645
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
analytical standard
Livello qualitativo
Saggio
≥97.0% (GC)
Durata
limited shelf life, expiry date on the label
applicazioni
cleaning products
cosmetics
food and beverages
personal care
Formato
neat
Stringa SMILE
OC1=C(CCCC)C=CC(O)=C1
InChI
1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3
CSHZYWUPJWVTMQ-UHFFFAOYSA-N
Descrizione generale
4-n-butylresorcinol is a derivative of resorcinol and a potent human tyrosinase inhibitor. It may be used to decrease skin irritation and is also known to inhibit melanin production.
Prodotti consigliati
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
293.0 °F
Punto d’infiammabilità (°C)
145 °C
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The efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma: a randomized controlled split-face trial.
Huh SY, et al.
Annals of Dermatology, 22(1), 21-25 (2010)
William Wargniez et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1060, 416-423 (2017-07-05)
In the present study, three laboratories independently compared percutaneous absorption and distribution of 4-n-butylresorcinol, using human skin from five donors. Each laboratory used the same protocol for percutaneous absorption studies but different LC-MS/MS analytical methods to quantify the test compound.
S-J Lee et al.
International journal of cosmetic science, 39(3), 248-255 (2016-10-27)
4-n-butylresorcinol is a competitive inhibitor of tyrosinase and has been used as an antimelanogenic agent. However, its inhibition mechanism in intact cells is not fully understood. To elucidate the cellular mechanism, we compared in vitro and in vivo inhibitory effects
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