45706

Warfarin

PESTANAL^®, analytical standard

• Sinonimo/i: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin, Coumafene
• Formula empirica (notazione di Hill): C₁₉H₁₆O₄
• Numero CAS: 81-81-2
• Peso molecolare: 308.33
• Beilstein: 8868198
• Numero CE: 201-377-6
• Numero MDL: MFCD00006854
• Codice UNSPSC: 41116107
• ID PubChem: 329756915
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Nome Commerciale: PESTANAL^®
• Durata: limited shelf life, expiry date on the label
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Punto di fusione: 162-164 °C (lit.)
• applicazioni: agriculture; environmental
• Formato: neat
• Stringa SMILE: CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
• InChI: 1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3; PJVWKTKQMONHTI-UHFFFAOYSA-N
• Informazioni sul gene: human ... VKORC1(79001)

Descrizione

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food.

Azioni biochim/fisiol

Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z.

Avvertenza

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

Note legali

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H310 + H330,H360D,H372,H411
• Consigli di prudenza: P202 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Classi di pericolo: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1 Oral
• Organi bersaglio: Blood
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3