GF309

NT-4 Protein, Human Recombinant Animal Free

The Neurotrophin-4 protein (or NT-4 protein), also known as NT-5 protein, is a member of the NGF family of neuronal & epithelial growth factors.

• Sinonimo/i: NT4, Neurotrophin 4, Neurotrophin 4/5, NT4/5
• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: >98% (SDS-PAGE and HPLC)
• Impurezze: <0.1 μg/mg protein endotoxin (<1EU/μg)
• N° accesso NCBI: NM_006179.3
• N° accesso UniProt: P34130
• Condizioni di spedizione: dry ice

Descrizione

Descrizione generale

Neurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

Specificità

Cross Reactivty
Mouse, Rat

Qualità

Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.

Stato fisico

Recombinant animal free human NT-4 is manufactured using all non-animal reagents

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable