8.07491

Poli(etilenglicole)

6000, for synthesis

• Sinonimo/i: PEG
• Formula condensata: H(OCH₂CH₂)_nOH
• Numero CAS: 25322-68-3
• Numero MDL: MFCD00081839
• Codice UNSPSC: 13111021
• Numero indice EU: 500-038-2
• NACRES: NA.22

Proprietà

• Tensione di vapore: <0.01 hPa ( 20 °C)
• Livello qualitativo: 200
• Forma fisica: solid
• Temp. autoaccensione: 420 °C
• Potenza: 28000 mg/kg LD₅₀, oral (Rat); >20000 mg/kg LD₅₀, skin (Rabbit)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• Punto di fusione: 58-63 °C
• Temp. transizione: flash point 270 °C
• Densità: 1.2 g/cm³ at 20 °C
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2; LYCAIKOWRPUZTN-UHFFFAOYSA-N

Descrizione

Descrizione generale

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels, etc. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Applicazioni

Polyethylene glycol 6000 is a non-ionic surfactant that can be used as a structure-directing agent to prepare mesoporous γ-A_l2O₃. PEG 6000 induced the formation of the lamellate structure morphology of boehmite nanoparticles with improved textural properties such as high surface area, larger pore volume, and pore size. It is also used in drug formulations to enhance the dissolution rate of the poorly water-soluble drug molecule. PEG-6000 can also be used in the purification of nucleic acids via the selective precipitation method. This approach is economically cost-effective and faster than the commonly employed chromatographic purification method.

Risultati analitici

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 16 - 23
Average molecular mass: 5000 - 7000
Identity (IR): passes test

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 281.5 °F - closed cup
• Punto d’infiammabilità (°C): 138.6 °C - closed cup