89510

Poli(etilenglicole)

BioUltra, 8,000

• Sinonimo/i: PEG
• Formula condensata: H(OCH₂CH₂)_nOH
• Numero CAS: 25322-68-3
• Numero MDL: MFCD00081839
• Codice UNSPSC: 12352104
• ID PubChem: 24889230
• NACRES: NA.26

Proprietà

• Livello qualitativo: 200
• Nome Commerciale: BioUltra
• Stato: solid
• PM: M_r 7000-9000
• Impurezze: insoluble matter:, passes filter test; ≤0.001% peroxides (as H₂O₂):
• pH: 5.5-7.0 (25 °C, 50 mg/mL in H₂O)
• Punto di fusione: 61-64 °C
• Solubilità: H₂O: 50 mg/mL at 25 °C, clear, colorless
• Anioni in tracce: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Cationi in tracce: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤200 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 50 mg/mL in H₂O
• Assorbanza UV: λ: 260 nm A_max: 0.09; λ: 280 nm A_max: 0.03
• Stringa SMILE: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2; LYCAIKOWRPUZTN-UHFFFAOYSA-N

Descrizione

Descrizione generale

Poly(ethylene glycol) (PEG) is a polymer of ethylene glycol units and is hydrophilic in nature. PEG has high hydration capacity and is structurally flexible. PEG has advantage as a drug conjugate due to biocompatibility and nonexistence of steric hindrances in its structure.

Applicazioni

Poly(ethylene glycol) has been used:

• in the transformation buffer in yeast
• as a constituent of dengue virus isolation buffer
• for concentration of lentivirus particles
• in the crystallization of herpesvirus nuclear egress complex (NEC)

Azioni biochim/fisiol

The Food and Drug Administration (FDA) approved PEG as drug conjugates, is nonimmunogenic and safe. PEG is widely used as a reagent in biochemistry and molecular biology experiments. PEG conjugation improves solubility and dissolution of diabetes drug, Gliclazide. It is used in carbon nanotube functionalization. The presence of PEG 8000 in the tannin tree foliage improves metabolisable energy (ME) content and gas production.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)