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Merck
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Key Documents

437644

Sigma-Aldrich

Lipoproteins, Low Density, Human Plasma

Sinonimo/i:

LDL

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About This Item

Codice UNSPSC:
12352202
NACRES:
NA.25

Saggio

≥95% (of total lipoprotein content, electrophoresis)

Livello qualitativo

Forma fisica

liquid

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

do not freeze
protect from light

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Descrizione generale

A 10 mg vial contains ~2 mg of protein.
Native low density lipoproteins from human plasma. Cholesterol-carrier lipoprotein responsible for delivery of lipids (cholesterol) from liver to tissues. (Composition: 78-81% lipid; 19-22% protein. Note: 10 mg vial contains 2 mg of protein.)
Native low density lipoproteins from human plasma. Cholesterol-carrier lipoprotein responsible for delivery of lipids (cholesterol) from liver to tissues. Composition: 78-81% lipid; 19-22% protein.

Confezionamento

Please refer to vial label for lot-specific concentration.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In 150 mM NaCl, 0.01% EDTA, pH 7.4.

Nota sulla preparazione

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

This product does not contain preservatives, so it is recommended that it be used under a laminar flow hood. Following initial use, this product is stable for 1 week at 2-8°C.

Altre note

Foster, J.D., et al. 1993. Endocrinology132, 337.
Retsky, K.L., et al. 1993. J. Biol. Chem. 268, 1304.
Fielding, C.J. 1992. FASEB J. 6, 3162.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Jiawei Chen et al.
The Biochemical journal, 393(Pt 1), 255-265 (2005-09-22)
LOX-1, a receptor for ox-LDL (oxidized low-density lipoprotein), has recently been determined to play a critical role in the progression of atherosclerosis. LOX-1 expression (mRNA and protein) has been shown to be up-regulated by pro-atherogenic stimuli, such as ox-LDL and
Jean Baptiste Nyandwi et al.
International journal of molecular medicine, 49(5) (2022-03-23)
Endothelial dysfunction during diabetes has been previously reported to be at least in part attributed to increased oxidized low‑density lipoprotein (oxLDL) levels mediated by high glucose (HG) levels. Endothelial inflammation increases the adhesiveness of monocytes to the endothelium in addition
Lee D Chaves et al.
JCI insight, 6(11) (2021-04-30)
Patients with chronic kidney disease (CKD) and end-stage renal disease suffer from increased cardiovascular events and cardiac mortality. Prior studies have demonstrated that a portion of this enhanced risk can be attributed to the accumulation of microbiota-derived toxic metabolites, with

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