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Documenti fondamentali

L8039

Sigma-Aldrich

Lipoprotein, high density from human plasma

≥95% (SDS-PAGE), solution

Sinonimo/i:

α-Lipoprotein, HDL, High density lipoprotein

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About This Item

Numero CAS:
308068-14-6
Numero MDL:
MFCD00164407
Codice UNSPSC:
12352211
NACRES:
NA.25

Origine biologica

human plasma

Livello qualitativo

200

Saggio

≥95% (SDS-PAGE)

Stato

solution

Confezionamento

vial of 10 mg protein

tecniche

cell culture | mammalian: suitable

N° accesso UniProt

P02649
P02655
P04114

Gruppo funzionale

ester
phospholipid

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Informazioni sul gene

human ... APOB(338) , APOC2(344) , APOE(348)

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Azioni biochim/fisiol

High density lipoprotein (HDL) serves as the transit agent for cholesterol away from blood, tissues, and organs of the body to the liver, where cholesterol breakdown occurs. This process ultimately helps to remove cholesterol from the arteries. Colloquially known as the "good cholesterol", HDL makes up 20%-30% of the total cholesterol in the body.

HDL is used in cardiovascular research and the development of potential therapeutic approaches to cardiovascular risk management.

Stato fisico

Solution in 150 mM NaCl and 0.01% EDTA, pH 7.4.

Altre note

View more information on lipoprotein function and lipid transport at www.sigma-aldrich.com/enzymeexplorer

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLCM3480
SLCJ9769
SLCJ0232
SLCG5930
SLCF2760

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VLDL, human

Sigma-Aldrich

LP1

VLDL, human

Apolipoprotein A−I human recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Sigma-Aldrich

SRP4693

Apolipoprotein A−I human

Apolipoprotein A-I from human plasma ≥85% (SDS-PAGE), buffered aqueous solution

Sigma-Aldrich

A0722

Apolipoprotein A-I from human plasma

Apolipoprotein A-I, human

Sigma-Aldrich

ALP10-M

Apolipoprotein A-I, human

Tisha R Joy
Pharmacology & therapeutics, 135(1), 18-30 (2012-04-03)
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has been associated with a 25-30% reduction in cardiovascular disease risk. However, there still remains a significant and quantifiable risk. Since epidemiologic data have demonstrated that low levels of high-density lipoprotein cholesterol (HDL-C)
Kyung-Hyun Cho
Medicines (Basel, Switzerland), 8(7) (2021-08-07)
The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I
Mark J Cziraky et al.
Journal of managed care pharmacy : JMCP, 14(8 Suppl), S3-28 (2009-11-07)
Most clinicians recognize the importance of reducing low-density lipoprotein cholesterol (LDL-C) and, therefore, address this therapeutic need to decrease cardiovascular disease risk. In addition to the critical role that LDL-C plays, recent studies have shown the contribution of other lipid
Santiago Redondo et al.
Lipids in health and disease, 10, 175-175 (2011-10-12)
Epidemiologic studies indicate a strong inverse correlation between plasma levels of high-density lipoproteins (HDL) and cardiovascular disease (CVD). The most relevant cardioprotective mechanism mediated by HDL is thought to be reverse cholesterol transport (RCT). New insights in HDL biology and
Menno Hoekstra et al.
Current opinion in lipidology, 23(2), 127-132 (2012-01-21)
Scavenger receptor class B type I (BI) is primarily known for its role in the selective uptake of cholesteryl esters from HDL, the final step in reverse cholesterol transport. Here, we will discuss findings that highlight the recently established novel
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