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Key Documents

428026

Sigma-Aldrich

Latrunculin A

from Latrunculia magnifica, ≥85% (HPLC), liquid, actin polymerization inhibitor, Calbiochem

Sinonimo/i:

InSolution Latrunculin A, Latrunculia magnifica

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About This Item

Formula empirica (notazione di Hill):
C22H31NO5S
Peso molecolare:
421.55
Codice UNSPSC:
12352200
NACRES:
NA.77

product name

Latrunculin A, Latrunculia magnifica, InSolution, ≥85%, 1 mM in DMSO, marine toxin that disrupts microfilament organization in cultured cells

Livello qualitativo

100

Saggio

≥85% (HPLC)

Forma fisica

liquid

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

OK to freeze
desiccated (hygroscopic)
protect from light

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Descrizione generale

A cell-permeable marine toxin from the Red Sea sponge Latrunculia magnifica that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos.

Azioni biochim/fisiol

Cell permeable: yes
Primary Target
Inhibitor of microfilament-mediated processes in sperm, eggs, and embryos
Product does not compete with ATP.
Reversible: no

Confezionamento

Packaged under inert gas

Attenzione

Toxicity: Harmful (C)

Stato fisico

A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428021 in DMSO.

Ricostituzione

Following initial use, aliquot and freeze (-20°C).

Altre note

Ayscough, K.R., et al. 1997. J. Cell Biol.137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Schatten, G., et al. 1986. Exp. Cell Res.166, 191.
Spector, I., et al. 1983. Science219, 493.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

188.6 °F - (refers to pure substance)

Punto d’infiammabilità (°C)

87 °C - (refers to pure substance)

Certificati d'analisi (COA)

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