1.00574

NMP

for Peptide Synthesis

• Sinonimo/i: 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• Formula empirica (notazione di Hill): C₅H₉NO
• Numero CAS: 872-50-4
• Peso molecolare: 99.13
• Numero MDL: MFCD00003193
• Codice UNSPSC: 12352115
• Numero indice EU: 212-828-1
• NACRES: NA.22

Proprietà

• product name: 1-Methyl-2-pyrrolidone, for Peptide Synthesis
• Tensione di vapore: 0.32 hPa ( 20 °C)
• Livello qualitativo: 200
• Saggio: ≥99.7% (GC)
• Forma fisica: liquid
• Temp. autoaccensione: 245 °C
• Potenza: 3598 mg/kg LD₅₀, oral (Rat); 8000 mg/kg LD₅₀, skin (Rabbit)
• Limite di esplosione: 1.3-9.5 % (v/v)
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• P. eboll.: 202 °C/1013 hPa
• Punto di fusione: -24 °C
• Temp. transizione: flash point 91 °C
• Densità: 1.03 g/cm³ at 20 °C
• applicazioni: peptide synthesis
• Temperatura di conservazione: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3; SECXISVLQFMRJM-UHFFFAOYSA-N

Descrizione

Descrizione generale

N-methyl-2-pyrrolidone (NMP) is an organic solvent that finds applications in numerous industries, including petrochemicals, plastics, microelectronics, and to produce pigments, cosmetics, and drugs. It is commonly used worldwide as an organic solvent, intermediate, or surfactant in various industrial and consumer applications. The unique characteristics of NMP, including its ability to mix with water and organic solvents, and its temperature, polarity, and composition stability, make it a solvent of great interest in extractive distillation.

Applicazioni

1-Methyl-2-pyrrolidone can be used as a solvent during the peptide bond formation reactions.

Informazioni sulla sicurezza

• Pittogrammi: GHS07,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H315 - H319 - H335 - H360D
• Consigli di prudenza: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 195.8 °F - Pensky-Martens closed cup
• Punto d’infiammabilità (°C): 91 °C - Pensky-Martens closed cup