05-636-AF488
Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor™ 488 Conjugate Antibody
clone JBW301, from mouse, ALEXA FLUOR™ 488
Sinonimo/i:
Histone H2AX, H2a/x, Histone H2A.X
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Coniugato
ALEXA FLUOR™ 488
Forma dell’anticorpo
purified antibody
Tipo di anticorpo
primary antibodies
Clone
JBW301, monoclonal
Reattività contro le specie
human
Reattività contro le specie (prevista in base all’omologia)
vertebrates (based on 100% sequence homology)
tecniche
immunocytochemistry: suitable
Isotipo
IgG1
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
phosphorylation (pSer139)
Informazioni sul gene
human ... H2AX(3014)
Descrizione generale
Histone H2A.X is a variant of histone H2A, and is similarly associated with genomic DNA. However, histone is structurally different from other members of the H2A family in possessing a C-terminal tail that contains the Ser139 residue that is phosphorylated in response to breaks in double-stranded DNA. The phosphorylation of H2A.X is a rapid process that is mediated by ATM/ATR proteins.
Applicazioni
This Anti-phospho Histone H2A.X (Ser139) antibody, clone JBW301, Alexa Fluor™ 488 Conjugate is validated for use in ICC for the detection of phospho Histone H2A.X (Ser139).
Qualità
Evaluated by Immunocytochemistry in untreated (negative control) and Staurosporin treated HeLa cells.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected phospho-Histone H2A.X (Ser139) in Staurosporin treated HeLa cells, and not in untreated HeLa cells.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected phospho-Histone H2A.X (Ser139) in Staurosporin treated HeLa cells, and not in untreated HeLa cells.
Descrizione del bersaglio
17 kDa calculated
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
ALEXA FLUOR is a trademark of Life Technologies
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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