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Key Documents

840875C

Avanti

18:1 PA

Avanti Research - A Croda Brand

Sinonimo/i:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); DOPA; PA(18:1(9Z)/18:1(9Z))

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About This Item

Formula empirica (notazione di Hill):
C39H72O8PNa
Numero CAS:
Peso molecolare:
722.95
Codice UNSPSC:
51191904
NACRES:
NA.25

Descrizione

1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt), chloroform solution

Saggio

>99% (TLC)

Forma fisica

liquid

Confezionamento

pkg of 1 × 2.5 mL (840875C-25mg)
pkg of 2 × 20 mL (840875C-1g)
pkg of 2 × 4 mL (840875C-200mg)
pkg of 5 × 4 mL (840875C-500mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand

Concentrazione

10 mg/mL (840875C-25mg)
25 mg/mL (840875C-1g)
25 mg/mL (840875C-200mg)
25 mg/mL (840875C-500mg)

Tipo di lipide

cardiolipins
phospholipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

InChI

1S/C39H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44);/b19-17-,20-18-;/t37-;/m1./s1
KHDHADSEKGCPKW-ZBFGHDQJSA-N

Descrizione generale

18:1 PA (1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)) is a sodium salt of modified lipid which has phosphatidic acid group as the backbone.

Applicazioni

18:1 PA (1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)) has been used:
  • as a synthetic standard to identify the position of PA after iodine staining in phosphatidic acid assay by thin-layer chromatography (TLC)
  • as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions
  • as a lipid standard in radiolabeling analysis of phospholipids

Azioni biochim/fisiol

Phosphatidic acid (PA) serves as a lipid messenger. It plays a key role in mammalian target of rapamycin (mTOR) signaling.

Confezionamento

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840875C-1g)
5 mL Clear Glass Sealed Ampule (840875C-200mg)
5 mL Clear Glass Sealed Ampule (840875C-25mg)
5 mL Clear Glass Sealed Ampule (840875C-500mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Comunemente ordinati con questo prodotto

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Shutao Guo et al.
Journal of controlled release : official journal of the Controlled Release Society, 174, 137-142 (2013-11-28)
The poor solubility of cisplatin (CDDP) often presents a major obstacle in the formulation of CDDP in nanoparticles (NPs) by traditional methods. We have developed a novel method for synthesizing CDDP NPs taking advantage of its poor solubility. By mixing
Zhenping Cao et al.
Nature communications, 10(1), 5783-5783 (2019-12-21)
The gut microbiota represents a huge community of microorganisms that play essential roles in immune modulation and homeostasis maintenance. Microbiota transplantation is an important approach to prevent and treat disease as it can inhibit pathogen colonization and positively modulate bacterial
Shireesha Sankella et al.
The Journal of biological chemistry, 289(8), 4762-4777 (2014-01-16)
In this study we examined the role of phosphatidic acid (PA) in hepatic glucose production (HGP) and development of hepatic insulin resistance in mice that lack 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2). Liver lysophosphatidic acid and PA levels were increased ∼2- and
Taylor E Miller et al.
Biology open, 6(2), 176-186 (2016-12-25)
The removal of mRNA transcript poly(A) tails by 3'→5' exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known cellular deadenylases are the CCR4-NOT and PAN complexes, and poly(A)-specific ribonuclease (PARN). The physiological roles and regulation for PARN is
Xinhui Sun et al.
Cell cycle (Georgetown, Tex.), 14(5), 721-731 (2015-01-16)
It had been known for decades that primordial follicles in mammalian ovaries are assembled with definite numbers and represent the ovarian reserve throughout the reproductive life. Intra-oocyte PI3K/mTOR pathways have been indicated to play a central role on the activation

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