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Key Documents

810604P

Avanti

16:0-16 Doxyl PC

Avanti Research - A Croda Brand 810604P, powder

Sinonimo/i:

1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine

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About This Item

Formula empirica (notazione di Hill):
C46H90N2O10P
Numero CAS:
Peso molecolare:
862.19
Codice UNSPSC:
51321705
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

powder

Confezionamento

pkg of 1 × 1 mg (810604P-1mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 810604P

Tipo di lipide

ESR probes

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Descrizione generale

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

Applicazioni

16:0-16 Doxyl PC has been used as a spin probe in electron spin resonance spectroscopy.

Azioni biochim/fisiol

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Confezionamento

5 mL Clear Glass Sealed Ampule (810604P-1mg)

Nota sulla preparazione

Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Codice della classe di stoccaggio

11 - Combustible Solids


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