810604C
Avanti
16:0-16 Doxyl PC
Avanti Research™ - A Croda Brand 810604C
Sinonimo/i:
1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine
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About This Item
Formula empirica (notazione di Hill):
C46H90N2O10P
Numero CAS:
Peso molecolare:
862.19
Codice UNSPSC:
41141825
NACRES:
NA.25
Prodotti consigliati
Saggio
>99% (TLC)
Stato
liquid
Confezionamento
pkg of 1 × 1 mL (810604C-1mg)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand 810604C
Concentrazione
1 mg/mL (810604C-1mg)
Tipo di lipide
ESR probes
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Categorie correlate
Descrizione generale
1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine (16:0-16 Doxyl PC) is a spin labelled phospholipid.
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
Applicazioni
1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine (16:0-16 Doxyl PC) may be used:
- in bilayers or membranes to study the distribution of the lipid-attached doxyl electron paramagnetic resonance (EPR) spin label
- as spin-labelled lipid in multilamellar vesicles (MLVs) to measure membrane fluidity
- as a spin-labeled deep quencher in small unilamellar vesicles (SUVs) for nitroxide lipid quenching experiments
Confezionamento
5 mL Clear Glass Sealed Ampule (810604C-1mg)
Nota sulla preparazione
Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Organi bersaglio
Central nervous system, Liver,Kidney
Classe di pericolosità dell'acqua (WGK)
WGK 3
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