700052P
Avanti
22(R)-hydroxycholesterol-d7
Avanti Research™ - A Croda Brand
Sinonimo/i:
25,26,26,26,27,27,27-heptadeuterocholest-5-ene-3β,22R-diol
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About This Item
Formula empirica (notazione di Hill):
C27H39O2D7
Numero CAS:
Peso molecolare:
409.70
Codice UNSPSC:
41141804
NACRES:
NA.25
Prodotti consigliati
Descrizione
cholest-5-ene-3β,22(R)-diol-d7
Saggio
>99% (TLC)
Forma fisica
powder
Confezionamento
pkg of 1 × 1 mg (700052P-1mg)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand
applicazioni
lipidomics
metabolomics
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Descrizione generale
22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in the neonate brain. 22(R)-hydroxycholesterol-d7 is a deuterated form of 22(R)-hydroxycholesterol.
Azioni biochim/fisiol
22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimer′s disease and may be implicated in neuroinflammation and neurodegenerative diseases.
Confezionamento
5 mL Amber Glass Screw Cap Vial (700052P-1mg)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
11 - Combustible Solids
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