QBD10198

NHS-dPEG^®₁₂-biotin

• Sinonimo/i: NHS-PEG Linker, Polyethylene glycol
• Formula empirica (notazione di Hill): C₄₁H₇₂N₄O₁₈S
• Peso molecolare: 941.09
• Codice UNSPSC: 12161502
• ID PubChem: 329823889
• NACRES: NA.22

Proprietà

• Saggio: >90%
• Forma fisica: solid or viscous liquid
• Impiego in reazioni chimiche: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: amine reactive
• Architettura del polimero: shape: linear; functionality: monofunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)ON3C(CCC3=O)=O

Descrizione

Caratteristiche e vantaggi

NHS-dPEG^®₁₂-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG^®₁₂-biotin has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG^® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG^® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

Note legali

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable