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M0505

Sigma-Aldrich

Methylamine hydrochloride

≥98%

Sinonimo/i:

Methanaminium chloride, Methylamine monohydrochloride, Methylammonium chloride, Monomethylammonium chloride

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About This Item

Formula condensata:
CH3NH2 · HCl
Numero CAS:
593-51-1
Peso molecolare:
67.52
Beilstein:
3588822
Numero CE:
209-795-0
Numero MDL:
MFCD00012849
Codice UNSPSC:
12352100
ID PubChem:
57654342
NACRES:
NA.22

Livello qualitativo

200

Saggio

≥98%

Stato

powder or crystals

P. ebollizione

225-230 °C/15 mmHg (lit.)

Punto di fusione

231-233 °C (lit.)

Solubilità

H2O: 1 g in 10 mL, clear, colorless

Stringa SMILE

Cl[H].CN

InChI

1S/CH5N.ClH/c1-2;/h2H2,1H3;1H
NQMRYBIKMRVZLB-UHFFFAOYSA-N

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Descrizione generale

Methylamine hydrochloride is used as a buildingblock for the synthesis of various organic compounds.

Applicazioni

Methylamine hydrochloride can be used as a reactant to synthesize:
  • Betahistine via aza-Michael reaction with 2-vinylpyridine in water.
  • Azatripyrrolic and azatetrapyrrolic macrocycles by reacting with pyrrole and formaldehyde via base-catalyzed Mannich reaction.
  • Tetrahydropyridines via Aza-Diels–Alder reaction with dienes and aldehydes.
  • N-methylsecondary arylamines from aryl chlorides via nickel-catalyzed amination reaction.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

408.7 °F - closed cup

Punto d’infiammabilità (°C)

209.3 °C - closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCCC2164
BCBS8772V
BCCB6126
BCBZ5957
MKCH0290

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Ammoniomethyl trifluoroborates are very powerful reagents that can be used to access biologically relevant aryl- and heteroaryl-methylamine motifs via Suzuki-Miyaura cross-couplings. Until now, this method was limited to the production of tertiary and primary amines. The synthesis of a large
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